Lower extremity muscle power – A critical determinant of physical function in aging and multiple sclerosis
نویسندگان
چکیده
In aging, lower extremity muscle power is undoubtedly one of the most important parameters neuromuscular function implicating physical (e.g. walking capacity). However, no previous studies have examined combined effects aging and multiple sclerosis (MS) on concomitant with function. The aim this cross-sectional study was to examine potential decrements in pwMS vs. healthy controls (HC) across adult lifespan these outcomes. present explorative study, n = 42 (females 29 (69%); age 53 ± 12 years (mean SD), range 31–78; patient determined disease steps score 3.7 1.7, 0–7) 49 age-matched HC 34 56 16 years, 24–78) were enrolled, divided into groups young (≤ 44 years), middle-aged (45–59 old (≥ 60 years). Muscle obtained from bilateral leg press (PowerLegPressPeak) maximal chair rise (PowerChairRise) using a linear encoder. Associations assessed between measurements (5 x sit-to-stand (5STS); timed 25-foot-walk-test (T25FWT)). reduced (PowerLegPressPeak −23[−34:−12]% (mean[95%CI]); PowerChairRise −26[−35:−17]%) negatively associated advanced both (decline per decade −0.40 W.kg−1 −2.53 W.kg−1, respectively) −0.42 −2.03 respectively). strongly (r2range 0.45–0.61, p < 0.01) yet only moderately 0.18–0.39, 0.01). MS reveal substantial that accompanied by (and with) Consequently, should be viewed as clinically factor (i.e. critical determinant function) pwMS. We propose specifically targeted preventive rehabilitative exercise strategies, especially older
منابع مشابه
Comparison of different methods of core muscle fatigue on lower extremity function tests among female athletes
Despite the importance of core muscles in kinetic chains, the importance of each muscle compared to others has rarely been investigated. The purpose of this study was to compare the effect of each core muscle fatigue on lower extremity function tests. This quasi-experimental study with a pretest-posttest design was performed on 30 physical educations, female students with the mean age of 23.46±...
متن کاملPhysical examination and chronic lower-extremity ischemia: a critical review.
OBJECTIVE To determine the clinical utility of physical examination in patients with suspected chronic ischemia of the lower extremities. DATA SOURCES MEDLINE search (January 1966 to January 1997), personal files, and bibliographies of textbooks on physical diagnosis, surgery, and vascular surgery. STUDY SELECTION Both authors independently graded the studies as level 1, 2, or 3, according ...
متن کاملFinger and foot tapping as alternative outcomes of upper and lower extremity function in multiple sclerosis
BACKGROUND While magnetic resonance imaging contrast-enhancing lesions represent an excellent screening tool for disease-modifying treatments in relapsing-remitting multiple sclerosis (RRMS), this biomarker is insensitive for testing therapies against compartmentalized inflammation in progressive multiple sclerosis (MS). Therefore, alternative sensitive outcomes are needed. Using machine learni...
متن کاملSkeletal muscle power: a critical determinant of physical functioning in older adults.
Muscle power declines earlier and more precipitously with advancing age compared with muscle strength. Peak muscle power also has emerged as an important predictor of functional limitations in older adults. Our current working hypothesis is focused on examining lower extremity muscle power as a more discriminant variable for understanding the relationships between impairments, functional limita...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Experimental Gerontology
سال: 2021
ISSN: ['0531-5565', '1873-6815']
DOI: https://doi.org/10.1016/j.exger.2021.111347